IVF Treatment Using Single Sperm Was A Success

30.01.2012

Everyone knows it takes just one sperm and one egg to make a baby, but nature usually provides extra, just to be sure.
In the case of 9-month-old Kenley Schiraldi of Campbell, Ohio, however, there was no back-up for the biology, requiring instead what scientists – and her parents – call a modern-day miracle.
Kenley was born last April, the result of a long-shot infertility treatment, a case Cleveland Clinic IVF experts say is the first time a single sperm has been frozen, injected into a single egg, and resulted in a healthy pregnancy.
Nina Desai, director of the IVF laboratory at the Cleveland Clinic, hasn’t calculated the odds of Kenley’s conception, which occurred even though her father, Jason, produced no sperm in the regular way, and her mom had trouble producing eggs.
“It was like a shot in the dark,” said Desai, who has developed a ground-breaking technique that can find and store tiny amounts of sperm – or even just one – in a drop of fluid inside a straw as thin as a sewing needle. The sperm can then be frozen and later thawed for use in an in-vitro fertilization technique known as intracytoplasmic sperm injection, or ICSI.
The new method follows nearly two decades of efforts to save the smallest possible amounts of human sperm by storing the cells inside hamster eggs or on tiny nylon loops for easier retrieval later. It’s expected to be a boon for men with very low sperm counts, a severe form of the male factor infertility that can contribute to the 1 in 8 couples in the U.S. who struggle to conceive.

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International Reproductive Technologies Support Agency | Organization of IVF and ICSI programmes
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