New Cryopreservation Technology of Tissue Regeneration to Be Used in Reproductive Medicine

“A woman has given birth to two children after her fertility was restored using transplants of ovarian tissue” – Dutch doctors report.

Bergholdt’s success at conception gives hope to young women, which has taken chemotherapy treatment for cancer prevention, to preserve their fertility.

Stinne Bergholdt, when she was 27, was diagnosed with Ewing’s sarcoma, a type of bone cancer, in 2004. Since chemotherapy would put her in early menopause, Bergholdt decided to freeze part of her right ovary. She had previously had her entire left ovary removed due to an unrelated problem (a dermoid cyst).

Her cancer treatment succeeded but, as expected, also caused a premature menopause because of using drastic remedies.

In December 2005 after her recovery, doctors reimplanted 20 percent of the ovary and it gradually renewed its function. This successful operation was covered in the Human Reproduction medical journal, which is published by the European Society of Human Reproduction and Embryology (ESHRE).

In February 2007 after short course of stimulating hormonotherapy Stinne Bergholdt became pregnant and delivered her first daughter, Aviaja, through in-vitro fertilization.

2009 she turned to a reproductive clinic to undergo IVF procedures. But she was pleasantly shocked because her pregnancy test showed that she had got pregnant naturally with intercourse.

In October 2009 Stinne delivered her second girl, Lucca.

7 children have been born worldwide to women with ovary transplants; Stinne Holm Bergholdt of Denmark becomes first woman to give birth twice after ovary transplant.

Appeared in MIGnews.com.

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