5-day biopsy is ok for embyo

13.08.2013

Over the last several years Carolina Conceptions has been offering embryo biopsy to rule out chromosomal abnormalities and genetic diseases in future pregnancies.  One of the downsides of the technique was that biopsies were performed after 3 days of embryo culture, which was later discovered to limit the ability of the embryo to undergo normal development.  This actually reduced the chance of pregnancy, often erasing any advantage that was provided by the biopsy procedure. 

Now Carolina Conceptions can perform the biopsy on embryos during day 5 of culture and transfer chromosomally normal embryos to the uterus as early as the next afternoon. By postponing the day of biopsy, the embryos are less stressed by the procedure because there are more cells due to the extra time to develop.  Furthermore, several cells from the embryo are biopsied on day 5, rather than a single cell on day 3.  By examining several cells, we greatly improve the ability to get accurate results for the genetic analysis of each embryo.  Recent studies have shown that embryo development is not compromised by a day 5 biopsy, and the subsequent transfer of the genetically normal embryos is much more likely to result in a healthy pregnancy.

www.news-medical.net

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