The newest genetic diagnosis approved in Japan

26.11.2014

Commission of the Society of Obstetrics and Gynecology in Japan, approved a plan of clinical trials, under which will be checked all 23 pairs of human chromosomes to find the genetic defects in the fertilized egg.

The study will involve women who were unable to conceive after at least 3 attempts of in vitro fertilization, as well as those who have had two or more miscarriages.

Doctors will use a technology called "Array CGH", to select the fertilized eggs that have no genetic abnormalities, and implant them in the uterus. The purpose of the clinical trial is to determine whether a new method can help reduce the risk of miscarriages and increase the likelihood of having children.

The "Array CGH" method helps to detect anomalies in all 23 pairs of chromosomes. In other words, doctors can not only find chromosomal defects that lead to miscarriage, but also to diagnose diseases such as Down syndrome, as well as to determine the sex of the child.

Between the members of the commission ignite debate about how much doctors should tell their patients about the results. Some experts believe that the new method can create ethical problems, as it will encourage patients to choose the perfect children. At present, genetic diagnosis of fertilized eggs are only held if a woman has probability of a transmission severe genetic diseases to the child.

According to the head of the commission Minoru Irahara, the study will help to test how the method is effective in assisting women who want to have children. He also added that the study by no means violates the ethical principles.

Based on: newsland.com

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